Pre-Defined Objects

Objects defined by admiralonco that can be used as input for derivations

rsp_y no_data_n cb_y bor_cr bor_pr bor_sd bor_non_crpd bor_pd bor_ne no_data_missing crsp_y_cr crsp_y_pr cbor_cr cbor_pr

Pre-Defined Response Event Objects

death_event lastalive_censor pd_event lasta_censor rand_censor trts_censor

Pre-Defined Time-to-Event Source Objects

Utility Functions

Utilities for Formatting Observations

aval_resp()

Map Character Response Values to Numeric Values

Utilities for Dataset Checking

get_crpr_dataset()

Get CR Records Followed by PR That Lead to a Prior Error

signal_crpr()

Signal CR Records Followed by PR

Example Datasets

You can run admiral::use_ad_template() to produce additional datasets

admiral_adrs

Response Analysis Dataset

Superseded

Superseded functions have been replaced with more flexible functions that allow for construction of more diverse endpoints for a wider array of oncology indications, beyond solid tumor/RECIST. However, we will not be removing these functions from admiralonco in the near future and they will continue to be supported.

derive_param_bor()

Adds a Parameter for Best Overall Response (without confirmation)

derive_param_clinbenefit()

Adds a Parameter for Clinical Benefit

derive_param_confirmed_bor()

Adds a Parameter for Confirmed Best Overall Response

derive_param_confirmed_resp()

Adds a Parameter for Confirmed Response

derive_param_response()

Adds a Parameter Indicating If a Subject Had a Response before Progressive Disease

filter_pd()

Filter up to First PD (Progressive Disease) Date