computes delta HR BL Mean

computes delta HR BL Mean

compute_delta_hrblm(data, id_col = ID, hrbl_col = HRBL, deduplicate = TRUE)

Arguments

data

A data frame containing C-QT analysis dataset

id_col

An unquoted column name for subject ID

hrbl_col

An unquoted column name for baseline HR measurements, default is HRBL

deduplicate

Boolean, whether baseline values are duplicated over rows. If true duplicates will be removed from average

Value

data frame with deltaHRBL

Examples

compute_delta_hrblm(cqtkit_data_verapamil)
#> # A tibble: 643 × 25
#>       ID TRTG   DOSE DOSEU DOSEF  NTLD TAFD   CONC CONCU    RR  RRBL    HR  HRBL
#>    <dbl> <fct> <dbl> <chr> <fct> <dbl> <chr> <dbl> <chr> <dbl> <dbl> <dbl> <dbl>
#>  1  1001 Plac…     0 mg    0 mg    0.5 0.5 …     0 NA     968   851   62.0  70.5
#>  2  1002 Plac…     0 mg    0 mg    0.5 0.5 …     0 NA    1097. 1193.  54.7  50.3
#>  3  1003 Plac…     0 mg    0 mg    0.5 0.5 …     0 NA    1026.  923.  58.5  65.2
#>  4  1004 Plac…     0 mg    0 mg    0.5 0.5 …     0 NA     862.  883.  69.6  68.0
#>  5  1005 Plac…     0 mg    0 mg    0.5 0.5 …     0 NA    1060. 1126.  56.6  53.3
#>  6  1006 Plac…     0 mg    0 mg    0.5 0.5 …     0 NA     998   999   60.2  60.2
#>  7  1007 Plac…     0 mg    0 mg    0.5 0.5 …     0 NA     919.  909   65.4  66.1
#>  8  1008 Plac…     0 mg    0 mg    0.5 0.5 …     0 NA     827.  991   72.5  60.6
#>  9  1009 Plac…     0 mg    0 mg    0.5 0.5 …     0 NA     872.  798.  68.9  75.3
#> 10  1010 Plac…     0 mg    0 mg    0.5 0.5 …     0 NA    1070. 1071   56.1  56.0
#> # ℹ 633 more rows
#> # ℹ 12 more variables: HRBLM <dbl>, deltaHRBL <dbl>, QT <dbl>, QTBL <dbl>,
#> #   QTCB <dbl>, QTCBBL <dbl>, QTCBBLM <dbl>, deltaQTCBBL <dbl>, QTCF <dbl>,
#> #   QTCFBL <dbl>, QTCFBLM <dbl>, deltaQTCFBL <dbl>