Data from Age-Related Macular Degeneration (ARMD) clinical trial

armd0

Format

A data frame with 1107 rows and 8 columns:

subject

A factor with 240 levels: 1, 2, 3, 4, 5, ...

treat.f

A factor with 2 levels: Placebo, Active

visual0

An integer vector with values from 20 to 85

miss.pat

A factor with 9 levels: ----, ---X, --X-, --XX, -XX-, ...

time.f

A factor with 5 levels: Baseline, 4wks, 12wks, 24wks, 52wks

time

A numeric vector with values from 0 to 52

visual

An integer vector with values from 3 to 85

tp

A numeric vector with values from 0 to 4

Source

Pharmacological Therapy for Macular Degeneration Study Group (1997). Interferon alpha-IIA is ineffective for patients with choroidal neovascularization secondary to age-related macular degeneration. Results of a prospective randomized placebo-controlled clinical trial. Archives of Ophthalmology, 115, 865-872.

Details

The ARMD data arise from a randomized multi-center clinical trial comparing an experimental treatment (interferon-alpha) versus placebo for patients diagnosed with ARMD.

See also

Examples

data(armd0, package = "nlmeU")
summary(armd0)
#>     subject        treat.f       visual0         miss.pat        time.f   
#>  2      :   5   Placebo:570   Min.   :20.00   ----   :940   Baseline:240  
#>  4      :   5   Active :537   1st Qu.:45.00   ---X   : 96   4wks    :231  
#>  6      :   5                 Median :56.00   --XX   : 24   12wks   :227  
#>  7      :   5                 Mean   :54.91   --X-   : 16   24wks   :214  
#>  8      :   5                 3rd Qu.:66.00   -XXX   : 12   52wks   :195  
#>  9      :   5                 Max.   :85.00   X---   :  8                 
#>  (Other):1077                                 (Other): 11                 
#>       time           visual            tp       
#>  Min.   : 0.00   Min.   : 3.00   Min.   :0.000  
#>  1st Qu.: 4.00   1st Qu.:37.00   1st Qu.:1.000  
#>  Median :12.00   Median :51.00   Median :2.000  
#>  Mean   :17.09   Mean   :49.86   Mean   :1.903  
#>  3rd Qu.:24.00   3rd Qu.:63.00   3rd Qu.:3.000  
#>  Max.   :52.00   Max.   :85.00   Max.   :4.000  
#>