Facilities for running simulations from ordinary differential equation ('ODE') models, such as pharmacometrics and other compartmental models. A compilation manager translates the ODE model into C, compiles it, and dynamically loads the object code into R for improved computational efficiency. An event table object facilitates the specification of complex dosing regimens (optional) and sampling schedules. NB: The use of this package requires both C and Fortran compilers, for details on their use with R please see Section 6.3, Appendix A, and Appendix D in the "R Administration and Installation" manual. Also the code is mostly released under GPL. The 'VODE' and 'LSODA' are in the public domain. The information is available in the inst/COPYRIGHTS.
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Dependency Anatomy Guide
Understanding Dependency Borders
Dependencies are visually distinguished by their border styles to help you understand their relationship to the current package:
Direct Dependencies
Thick solid border: These are dependencies directly specified in the package's DESCRIPTION file (Depends, Imports, Enhances, or LinkingTo).
Recursive Dependencies
Thin solid border: These are dependencies of dependencies (recursive/indirect dependencies). They are initially hidden but can be toggled with the switch button.
Version Constraint Conflicts
Thick border + Info icon: When both direct and recursive dependencies exist for the same package with different version constraints. This indicates the "true" version constraint for the package, as the recursive dependency requires the more strict version constraint.
Understanding the Info Icon
The yellow info circle appears when there are version constraint conflicts between direct and recursive dependencies for the same package. This helps give a more accurate picture of the version constraints for the dependencies of a given package.