Calculate accumulation ratio This is the ratio of drug concentration or AUC at steady state over concentrations after single dose — accumulation_ratio • clinPK

Calculate accumulation ratio This is the ratio of drug concentration or AUC at steady state over concentrations after single dose

accumulation_ratio(kel = NULL, halflife = NULL, tau = 24)

Arguments

kel: drug elimination rate
halflife: halflife. Either `kel` or `halflife` is required.
tau: dosing interval

Examples

accumulation_ratio(halflife = 24, tau = 24)
#> [1] 2
accumulation_ratio(kel = 0.08, tau = 12)
#> [1] 1.620464