Calculate dose to achieve steady state Cmax for 1-compartmental PK model with infusion dosing at steady state

Calculate dose to achieve steady state Cmax for 1-compartmental PK model with infusion dosing at steady state

pk_1cmt_inf_dose_from_cmax(cmax = 1, tau = 12, t_inf = 1, CL = 3, V = 30)

Arguments

cmax

desired trough concentration

tau

dosing interval

t_inf

infusion time

CL

clearance

V

volume of distribution

Examples

pk_1cmt_inf_dose_from_cmax(cmax = 20, tau = 12, t_inf = 2, CL = 5, V = 50)
#> [1] 771.0142