Plots residuals vs predicted dQTCF and concentration

Plots residuals vs predicted dQTCF and concentration

gof_residuals_plots(
  data,
  fit,
  dv_col,
  conc_col,
  ntime_col,
  trt_col = NULL,
  conc_xlabel = "Concentration (ng/mL)",
  dv_label = bquote(Delta ~ "QTc (ms)"),
  residual_references = c(-2, 2),
  legend_location = c("top", "bottom", "left", "right", "none"),
  style = list()
)

Arguments

data

A data frame containing C-QT analysis dataset

fit

An nlme::lme model object from model fitting

dv_col

An unquoted column name for dependent variable measurements

conc_col

An unquoted column name for drug concentration measurements

ntime_col

An unquoted column name for nominal time since dose

trt_col

An unquoted column name for treatment group"

conc_xlabel

A string of concentration xlabel

dv_label

A string of dv label (default: bquote(Delta ~ 'QTc (ms)'))

residual_references

Numeric vector of reference residual lines to add, default -2 and 2

legend_location

String for legend position (top, bottom, left, right)

style

A named list of arguments passed to style_plot()

Value

a plot

Examples

data_proc <- preprocess(cqtkit_data_verapamil)
fit <- fit_prespecified_model(
  data_proc,
  deltaQTCF,
  ID,
  CONC,
  deltaQTCFBL,
  TRTG,
  TAFD,
  "REML",
  TRUE
)
gof_residuals_plots(
  data_proc,
  fit,
  deltaQTCF,
  CONC,
  NTLD,
  TRTG,
  legend_location = "top")