armd.wide Data (240 x 10)

Source: R/nlmeU-package.R

Data from Age-Related Macular Degeneration (ARMD) clinical trial

armd.wide

Format

A data frame with 240 rows and 10 columns:

subject

A factor with 240 levels: 1, 2, 3, 4, 5, ..., 240

lesion

An integer vector with values 1, 2, 3, 4

line0

An integer vector with values ranging from 5 to 17

visual0

An integer vector with values of visual acuity measured at baseline ranging from 20 to 85

visual4

An integer vector with values of visual acuity measured at 4 weeks ranging from 12 to 84

visual12

An integer vector with values of visual acuity measured at 12 weeks ranging from 3 to 85

visual24

An integer vector with values of visual acuity measured at 24 weeks ranging from 5 to 85

visual52

An integer vector with values of visual acuity measured at 52 weeks from 4 to 85

treat.f

A factor with 2 levels: Placebo, Active

miss.pat

A factor with 9 levels: ----, ---X, --X-, --XX, -XX-, ..., XXXX

Source

Pharmacological Therapy for Macular Degeneration Study Group (1997). Interferon alpha-IIA is ineffective for patients with choroidal neovascularization secondary to age-related macular degeneration. Results of a prospective randomized placebo-controlled clinical trial. Archives of Ophthalmology, 115, 865-872.

Details

The ARMD data arise from a randomized multi-center clinical trial comparing an experimental treatment (interferon-alpha) versus placebo for patients diagnosed with ARMD.

See also

armd, armd0

Examples

data(armd.wide, package = "nlmeU")
summary(armd.wide)
#>     subject        lesion          line0         visual0         visual4     
#>  1      :  1   Min.   :1.000   Min.   : 5.0   Min.   :20.00   Min.   :12.00  
#>  2      :  1   1st Qu.:1.000   1st Qu.: 9.0   1st Qu.:45.00   1st Qu.:42.00  
#>  3      :  1   Median :2.000   Median :11.0   Median :56.50   Median :53.00  
#>  4      :  1   Mean   :1.891   Mean   :10.9   Mean   :54.95   Mean   :52.46  
#>  5      :  1   3rd Qu.:2.500   3rd Qu.:13.0   3rd Qu.:66.00   3rd Qu.:64.00  
#>  6      :  1   Max.   :4.000   Max.   :17.0   Max.   :85.00   Max.   :84.00  
#>  (Other):234   NA's   :1                                      NA's   :9      
#>     visual12        visual24        visual52        treat.f       miss.pat  
#>  Min.   : 3.00   Min.   : 5.00   Min.   : 4.00   Placebo:119   ----   :188  
#>  1st Qu.:39.50   1st Qu.:36.00   1st Qu.:27.00   Active :121   ---X   : 24  
#>  Median :52.00   Median :47.00   Median :40.00                 --XX   :  8  
#>  Mean   :50.84   Mean   :47.49   Mean   :41.97                 -XXX   :  6  
#>  3rd Qu.:64.50   3rd Qu.:62.00   3rd Qu.:56.50                 XXXX   :  6  
#>  Max.   :85.00   Max.   :85.00   Max.   :85.00                 --X-   :  4  
#>  NA's   :13      NA's   :26      NA's   :45                    (Other):  4