All functions

addCwres()

Add CWRES

addNpde()

NPDE calculation for nlmixr2

addTable()

Add table information to nlmixr2 fit object without tables

assertNlmixrFit()

Assert that this is a nlmixr2 fit object

assertNlmixrFitData()

Assert that this is a nlmixr2 fit data object

bobyqaControl()

Control for bobyqa estimation method in nlmixr2

boxCox() iBoxCox() yeoJohnson() iYeoJohnson()

Cox Box, Yeo Johnson and inverse transformation

cholSE()

Generalized Cholesky Matrix Decomposition

.augPredIpredModel()

Augment Prediction for Ipred Model

.nlmixrPreprocessLiteralFix()

This literally fixes parameters in the model

.preProcessDataUi()

Preprocess the zero omegas

.preProcessZeroOmega()

Preprocess the zero omegas

foceiControl()

Control Options for FOCEi

getValidNlmixrControl() getValidNlmixrCtl()

Get valid nlmixr control object

lbfgsb3cControl()

Control for lbfgsb3c estimation method in nlmixr2

n1qn1Control()

Control for n1qn1 estimation method in nlmixr2

newuoaControl()

Control for newuoa estimation method in nlmixr2

nlmControl()

nlmixr2 defaults controls for nlm

nlminbControl()

nlmixr2 nlminb defaults

nlmixr2() nlmixr()

nlmixr2 fits population PK and PKPD non-linear mixed effects models.

nlmixr2AllEst()

Show all the current estimation methods

nlmixr2AugPredSolve() augPred(<nlmixr2FitData>)

Augmented Prediction for nlmixr2 fit

nlmixr2CreateOutputFromUi()

Create nlmixr output from the UI

nlmixr2Est()

Generic for nlmixr2 estimation methods

nlmixr2Gill83()

Get the optimal forward difference interval by Gill83 method

nlmixr2Hess()

Calculate Hessian

nlmixr2Keywords

A list and description of the fields in the nlmxir2 object

nlmixr2Logo()

Messages the nlmixr2 logo...

nlmixr2NlmeControl() nlmeControl()

Control Values for nlme Fit with extra options for nlmixr

nlmixr2Validate() nmTest()

Validate nlmixr2

nlmixr2Version()

Display nlmixr2's version

nlmixrAddObjectiveFunctionDataFrame()

Add objective function data frame to the current objective function

nlmixrAddTiming()

Manually add time to a nlmixr2 object

nlmixrCbind()

nlmixrCbind

nlmixrClone()

Clone nlmixr environment

nlmixrWithTiming()

Time a part of a nlmixr operation and add to nlmixr object

nlsControl()

nlmixr2 defaults controls for nls

nmNearPD()

C++ implementation of Matrix's nearPD

nmObjGetControl()

Get control object from fit

nmObjGetEstimationModel()

Get the estimation model for a fit object depending on the object type

nmObjGetFoceiControl()

Method for getting focei compatible control object from nlmixr object

nmObjGetIpredModel() nmObjGetEstimationModel(<saem>) nmObjGetEstimationModel(<default>)

Get the ipred model for a fit object depending on the object type

nmObjGetPredOnly()

Get the pred-only model for a fit depending on the object type

nmObjHandleControlObject()

Handle the control object

nmObjHandleModelObject()

Handle Model Object

nmObjUiSetCompressed()

Set if the nlmixr2 object will return a compressed ui

nmsimplex()

Nelder-Mead simplex search

ofv()

Return the objective function

optimControl()

nlmixr2 optim defaults

print(<saemFit>)

Print an SAEM model fit summary

residuals(<nlmixr2FitData>)

Extract residuals from the FOCEI fit

saemControl()

Control Options for SAEM

setCov()

Set the covariance type based on prior calculated covariances

setOfv() getOfvType()

Set/get Objective function type for a nlmixr2 object

sqrtm()

Return the square root of general square matrix A

summary(<saemFit>)

Print an SAEM model fit summary

tableControl()

Output table/data.frame options

uobyqaControl()

Control for uobyqa estimation method in nlmixr2

vpcSim()

VPC simulation