Control options for log-likelihood profiling
llpControl(
ofvIncrease = qchisq(0.95, df = 1),
rseTheta = 30,
itermax = 10,
ofvtol = 0.005,
paramDigits = 3,
extrapolateExpand = 1.5
)
The targetted change in objective function value (3.84 corresponds to a Chi-squared test with a 95% confidence interval)
The relative standard error (percent) for the model parameters. It can be missing (the default) in which case a default value of 30% will be applied. If given as a single number, it will be applied to all parameters. If given as a named vector of numbers, it will be applied to each named parameter.
Maximum number of likelihood profiling iterations for each bound estimated
The relative tolerance for the objective function being close
enough to the ofvIncrease
.
The number of significant digits required for the parameter. When interpolation attempts to get smaller than that number of significant digits, it will stop.
When extrapolating outside the range previously tested, how far should the step occur as a ratio
A validated list of control options for log-likelihood profiling
Other Profiling:
fixedControl()
,
profile.nlmixr2FitCore()
,
profileFixed()
,
profileLlp()
,
profileNlmixr2FitCoreRet()